Government work and is in the public domain in the USA. It is difficult to predict early on who will acknowledge new risks over the course of pregnancy, and thus all women should be screened repeatedly to allow for the identification of risks and intervention during prenatal care.Īfrican American pregnancy psychosocial risk.Ģ013 RCOG Published 2013. Among these, only education less than high school was associated with the acknowledgement of new risk in the bivariate analyses, and significantly predicted the identification of new risks (OR 1.39, 95% CI 1.01-1.90). The psychosocial variables collected at the baseline that were entered into the logistic regression model included relationship status, education, Medicaid, illicit drug use, and alcohol use during pregnancy. Reported smoking increased by 11%, environmental tobacco smoke exposure increased by 19%, intimate partner violence increased by 9%, and depression increased by 20%. Repeated screening identified more mothers acknowledging risk over time. New risks: psychosocial variables to understand what factors might help identify the acknowledgement of additional risk(s). Standard hypothesis tests and logistic regression were used to predict the acknowledgment of any new risk(s) during pregnancy. Risks were considered new if they were not previously reported. Mothers were classified by their initial response (acknowledgement of risks), and these data were updated during pregnancy. Prenatal care sites in the District of Columbia serving mainly women of minority background.Ī cohort of 1044 African American pregnant women in the District of Columbia. SEQUENTIAL TESTING PREGNANCY TRIALThis prospective longitudinal analysis examines the added benefit of repeated screening, compared with a single screening, in identifying such risks during pregnancy.ĭata were collected as part of a randomised controlled trial to address intimate partner violence, depression, smoking, and environmental tobacco smoke exposure in African American women. 2012 119(5):890-901.Screening for psychosocial and behavioural risks, such as depression, intimate partner violence, and smoking, during pregnancy is considered to be state of the art in prenatal care. Genome-wide fetal aneuploidy detection by maternal plasma DNA sequencing. Bianchi DW, Platt LD, Goldberg JD, Abuhamad AZ, Sehnert AJ, Rava RP.CARE Study Group: DNA sequencing versus standard prenatal aneuploidy screening. (cfDNA) screening has impacted prenatal testing. Bianchi DW, Parker RL, Wentworth J, et al. prenatal screening, noninvasive prenatal testing, sequential screening.Noninvasive prenatal screening for fetal aneuploidy, 2016 update: a position statement of the American College of Medical Genetics and Genomics. Gregg AR, Skotko BG, Benkendorf JL, et al.Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing. Chen EZ, Chiu RW, Sun H, Akolekar R, Chan KC, Leung TY, Jiang P, Zheng YW, Lun FM, Chan LY, Jin Y, Go AT, Lau ET, To WW, Leung WC, Tang RY, Au-Yeung SK, Lam H, Kung YY, Zhang X, van Vugt JM, Minekawa R, Tang MH, Wang J, Oudejans CB, Lau TK, Nicolaides KH, Lo YM.Analysis of cell-free DNA in maternal blood in screening for fetal aneuploidies: updated meta-analysis. Gil MM, Accurti V, Santacruz B, Plana MN, Nicolaides KH.Position statement from the Aneuploidy Screening Committee on behalf of the Board of the International Society for Prenatal Diagnosis.
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